Here's some real off cabinet screens.
You can probably get by with 640x480 if you have a tri sync monitor:
But 320x224 is basically unsuable:
A lot of guides will tell you to run games using horizontal super resolutions. I don't. There's a noticeable quality difference. Here's Super Turbo with Final Burn set to exact cps2 resolution. Also FB has a setting for which monitor to use for full screen that basically doesn't work. You need to set your cabinet monitor to the primary monitor in windows. Anyway the picture is perfect.
Tl;dr don't expect a hassle free gaming experience trying to use Fightcade on a cabinet. You need a second monitor, mouse, and keyboard handy, and there will be settings to diddle.