So the deluxe versions of Airline Pilots and Strike Fighter had 3 CRTs each, and each monitor got it's own NAOMI (since it needs to generate 3X the graphics). There were normal single monitor versions of these games that only used 1 NAOMI.
F355 Challenge 1&2 went a step further. the normal, single monitor F355 Challenge NAOMI was a special version had 2 NAOMI mobo's in the same housing for double the power. AFAIK it's the only game like this. Then the triple monitor deluxe version had even more (I'm not sure exactly how many)... so yeah, that's a lot of NAOMIs.
From what I understand other games wont run on these setups, and even if they did, they wouldn't benefit from the extra power because they wouldn't be programmed to utilize it.